What scientists long believed were knots in DNA may actually be persistent twists formed during nanopore analysis, revealing ...

- Research published in Molecular Cell used INDUCE-seq to identify DNA topology as an important regulator of CRISPR targeting specificity - Peer-reviewed data demonstrates the sensitivity of ...

For decades, biology textbooks taught that DNA’s story could be told with a single image: two elegant strands twisting in a ...

Human life hinges on the ability of our cells to cram six feet of DNA into a 10-micron nucleus—equivalent to fitting a mile of string inside one green pea. But stuffing genes into cramped quarters is ...

Researchers have discovered how cells activate a last-resort DNA repair system when severe damage strikes. When genetic ...

It's a common storytelling trope: the stubborn foe who is eventually revealed to be a much-needed friend. Biology has its own ...

When does DNA behave like sand or toothpaste? When the genetic material is so densely packed within a virus, it can behave like grains of sand or toothpaste in a tube. That's essentially what ...

Broken String Biosciences (“Broken String”), a genomics company building a technology platform to drive the development of cell and gene therapies that are safer by design, today announced that its ...

Human life hinges on the ability of our cells to cram six feet of DNA into a 10-micron nucleus -- equivalent to fitting a mile of string inside one green pea. But stuffing genes into cramped quarters ...