Studies of the aetiology of glioma, the commonest malignant brain tumour, with a very poor prognosis, are urgently needed, specifically to identify modifiable risk factors. The main reason that ...

Objectives The objective of this paper is to show the benefits of using a 2-phase case—control (2PCC) design in identifying dose—response relationships between cumulative occupational exposure as ...

A case-control study is a type of medical research investigation often used to help determine the cause of a disease, particularly when investigating a disease outbreak or rare condition. If public ...

We detail study design options that generalize case–control sampling when longitudinal outcome data are already collected as part of a primary cohort study, but new exposure data must be ...

Correspondence to Dr Brent E Hagel, Department of Paediatrics, Cumming School of Medicine, University of Calgary, Calgary, AB T2N 1N4, Canada; brent.hagel{at}albertahealthservices.ca Background ...

Objectives: Case management is commonly used by health plans to attempt to improve the care received by their members who have complex needs, such as those who undergo transplantation. There are few ...